XBP-1 Monoclonal Antibody

This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively e

Introducing the XBP-1 Monoclonal Antibody, a cutting-edge scientific tool designed to revolutionize research in the field of immunology. This highly specific antibody is meticulously engineered to target and bind to the XBP-1 protein, enabling researchers to gain invaluable insights into the intricate mechanisms of cellular stress response and unfolded protein response pathways.

Crafted with utmost precision and utilizing state-of-the-art technology, the XBP-1 Monoclonal Antibody boasts exceptional affinity and selectivity, ensuring accurate and reliable results in a wide range of experimental applications. Its robust performance guarantees optimal detection and quantification of XBP-1 protein expression, facilitating comprehensive investigations into its role in various physiological and pathological processes.

The XBP-1 Monoclonal Antibody is meticulously validated through rigorous quality control measures, ensuring consistent and reproducible results across experiments. Its exceptional sensitivity allows for the detection of even low levels of XBP-1 protein, enabling researchers to delve deeper into the intricate molecular pathways involved in cellular stress response.

With its user-friendly format, the XBP-1 Monoclonal Antibody offers unparalleled ease of use, making it suitable for both seasoned researchers and newcomers to the field. Its compatibility with a variety of experimental techniques, including Western blotting, immunohistochemistry, and flow cytometry, further enhances its versatility and applicability in diverse research settings.

In summary, the XBP-1 Monoclonal Antibody represents a breakthrough in immunological research, providing scientists with a powerful tool to unravel the complexities of cellular stress response pathways. With its exceptional specificity, sensitivity, and ease of use, this antibody is poised to drive groundbreaking discoveries and advance our understanding of fundamental biological processes.